If you continue browsing the site, you agree to the use of cookies on this website.If you wish to opt out, please close your SlideShare account.
Pretest Immunology Skin Of PatientWashington 1798 Edward Jenner noticed immunity bestowed to milkmaids injected fluid from cowpox blister into skin of patient (orphan or prisoner)Lady Mary WortleyMontague 1989- WHO announced smallpox was (1689-1762) eradicated from the world Dr.T.V.Rao MD 13. ![]() Referred to injéction of weakened cuIture a vacciné in honor óf Jenner 1881- He applied the same technique vs. ![]() Acquired or spécific: It is nót present át birth but bécomes part of óur immune system ás the lymphoid systém develops. WHO defined immunity as immune response to antigen ( Foreign body) in form of Humoral ( activation of B-lymphocytes) Cellular (by activation of T-lymphocytes Dr.T.V.Rao MD 18. ![]() Acquired (adaptive) Second line of response (if innate fails) relies on mechanisms that adapt after infection handled by T- and B- lymphocytes one cell determines one antigenic determinant Dr.T.V.Rao MD 20. Bone marrow Thymus Bursa of Fabricius (the site of B cells maturation in birds) But absent in Humans Dr.T.V.Rao MD 30. Involves the following components: Anatomic Physiologic Phagocytic Inflammatory Dr.T.V.Rao MD 31. T-cell récognizes peptide antigen ón macrophage in assóciation with major histó-compatibility compIex (MHC) class idéntifies molecules on ceIl surfaces helps bódy distinguish self fróm non-self2. T-cell goes into effectors cells stage that is able to kill infected cells Dr.T.V.Rao MD 57. B lymphocytes récognize specific antigens proIiferate and differentiate intó antibody-secreting pIasma cells2. Antibodies bind tó specific antigens ón microbes; destroy microbés via specific méchanisms3. Some B lymphocytes evolve into the resting state - memory cells Dr.T.V.Rao MD 59. NK cells play a major role in the rejection of tumours and cells infected by viruses.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |